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Leiden University

A gift from Orange, sixteen Nobel Prizes later.

Photo: By https://imgur.com/r/europe/VnJxiYD, Public Domain, https://commons.wikimedia.org/w/index.php?curid=77289333

The story of Leiden University

In 1575 William of Orange gave Leiden a university. Almost five centuries later it is one of the oldest and best-known universities in Europe. Sixteen Nobel laureates studied, earned their doctorate, taught or worked there, and three generations of the royal family sat in its lecture halls.

Leiden became a city of knowledge. In the 17th century students came from all over Europe, and Rembrandt and René Descartes both enrolled. The university built a botanical garden, an observatory and an anatomy theatre. Around 1900 physics made Leiden world-famous: Lorentz, Zeeman and Kamerlingh Onnes won the Nobel Prize, and Kamerlingh Onnes' laboratory was the first in the world to liquefy helium. Albert Einstein was a professor by special appointment. The brothers Jan and Niko Tinbergen both won a Nobel Prize, one for economics, the other for medicine. The timeline below shows all sixteen laureates with a Leiden connection, following the university's own list. Many of their instruments are on show at Rijksmuseum Boerhaave.

  • 1575founded by William of Orange
  • 16Nobel laureates with a Leiden connection
  • 1908liquid helium for the first time in the world

Orange's greatest gift

A university is a gift that keeps on giving. What William of Orange gave Leiden in 1575 still enriches the Netherlands and the world almost 450 years later.

  • Knowledge for everyoneFor almost five centuries young people from the Netherlands and all over the world have studied here. In 2025 the university celebrated its 450th anniversary.
  • Discoveries that changed the worldSixteen Nobel Prizes, the ECG, liquid helium and superconductivity: ideas from Leiden live on in hospitals, laboratories and technology worldwide.
  • Heritage you can visit todayThe Hortus botanicus, the Old Observatory and Rijksmuseum Boerhaave, which grew out of the university's collections, are open to everyone.
  • A haven for thinkersIn Leiden scholars such as Descartes could think and write freely, and the Pilgrims found a home before sailing to America.
  • A bond that lastsThree generations of the House of Orange studied in Leiden: Juliana, Beatrix and Willem-Alexander.

From Orange to the Nobel Prize

The university's great moments and all sixteen Nobel laureates with a Leiden connection. Pick a colour to follow one story.

  1. 1575
    House of Orange

    A university as a reward

    After the siege of Leiden, William of Orange founds the first university of the northern Netherlands.

    See it at: Academy Building, Rapenburg
  2. 1590
    Science

    The Hortus botanicus

    The university lays out a physic garden. A few years later Carolus Clusius plants the first tulips there.

    See it at: Hortus botanicus Leiden →
  3. 1620
    Art & ideas

    Rembrandt enrols

    The young Rembrandt van Rijn is registered as a student, but soon chooses painting instead.

    See it at: Museum De Lakenhal →
  4. 1630
    Art & ideas

    Descartes in Leiden

    French philosopher René Descartes enrols to study mathematics. He lived in the Dutch Republic for some twenty years.

    See it at: Academy Building, Rapenburg
  5. 1633
    Science

    An observatory on the roof

    Leiden gets one of the first university observatories in the world.

    See it at: Old Observatory
  6. 1709
    Science

    Boerhaave, teacher of Europe

    Herman Boerhaave becomes professor. His bedside teaching draws students from all over Europe.

    See it at: Rijksmuseum Boerhaave →
  7. 1901
    Nobel Prize

    Van 't Hoff – Chemistry

    Jacobus van 't Hoff, the very first Nobel laureate in chemistry, studied in Leiden.

  8. 1902
    Nobel Prize

    Lorentz and Zeeman – Physics

    Hendrik Lorentz, professor in Leiden, and his former student Pieter Zeeman share the prize for their work on light and magnetism.

    See it at: Rijksmuseum Boerhaave →
  9. 1908
    Science

    Liquid helium

    Heike Kamerlingh Onnes' laboratory liquefies helium for the first time in the world. Leiden becomes the coldest place on earth.

    See it at: Rijksmuseum Boerhaave →
  10. 1910
    Nobel Prize

    Van der Waals – Physics

    Johannes Diderik van der Waals studied and earned his doctorate in Leiden.

  11. 1911
    Nobel Prize

    Asser – Peace

    Tobias Asser, who earned his doctorate in Leiden, receives the Nobel Peace Prize for his work on international law.

  12. 1913
    Nobel Prize

    Kamerlingh Onnes – Physics

    The Leiden professor who discovered superconductivity wins the prize for his research into extreme cold.

    See it at: Rijksmuseum Boerhaave →
  13. 1921
    Nobel Prize

    Einstein – Physics

    Albert Einstein is professor by special appointment in Leiden from 1920 to 1946, and a close friend of physicist Paul Ehrenfest.

  14. 1924
    Nobel Prize

    Einthoven – Medicine

    Leiden professor Willem Einthoven invents the electrocardiogram, the ECG.

    See it at: Rijksmuseum Boerhaave →
  15. 1927
    House of Orange

    Princess Juliana studies in Leiden

    The first of three generations of the House of Orange at Leiden University.

    See it at: Academy Building, Rapenburg
  16. 1937
    Nobel Prize

    Szent-Györgyi – Medicine

    The discoverer of vitamin C did research in Leiden in the early 1920s.

  17. 1938
    Nobel Prize

    Fermi – Physics

    Enrico Fermi worked in Leiden on a fellowship in 1924.

  18. 1956
    House of Orange

    Princess Beatrix studies in Leiden

    The future queen studies law here until 1961. In 2005 the university awards her an honorary doctorate.

    See it at: Academy Building, Rapenburg
  19. 1958
    Nobel Prize

    Tamm – Physics

    Russian physicist Igor Tamm was a visiting researcher in Leiden in 1928.

  20. 1969
    Nobel Prize

    Jan Tinbergen – Economics

    Leiden student and doctoral candidate, and winner of the very first Nobel Prize in economics.

  21. 1973
    Nobel Prize

    Niko Tinbergen – Medicine

    His brother, a Leiden student, lecturer and professor, wins the prize for his research into animal behaviour.

  22. 1975
    Nobel Prize

    Koopmans – Economics

    Tjalling Koopmans earned his doctorate in Leiden in 1936.

  23. 1981
    Nobel Prize

    Bloembergen – Physics

    Nicolaas Bloembergen earned his doctorate in Leiden in 1948; his prize was for laser spectroscopy.

  24. 1984
    Nobel Prize

    Jerne – Medicine

    Niels Jerne studied in Leiden and won the prize for his work on the immune system.

  25. 1987
    House of Orange

    Willem-Alexander studies in Leiden

    The future king studies history here.

    See it at: Academy Building, Rapenburg

Your museum day in Leiden University

One day, four moments. How to get the most out of your visit.

  1. 10:00MUSEUM
    Rijksmuseum Boerhaave Start with the Nobel laureates' instruments.
  2. 12:30EAT
    Lunch on the Nieuwe Rijn Waterside terraces among the students.
  3. 15:30SHOP
    Haarlemmerstraat and the bookshops A university town full of antiquarian and new bookshops.
  4. 19:00SLEEP
    A hotel in the old centre An evening walk along the Rapenburg.

What to do in Leiden University

Six places to complete your museum day.

  1. 01

    Rijksmuseum Boerhaave →

    The museum of science, with instruments from Leiden's Nobel laureates, Kamerlingh Onnes' cold lab and a reconstructed anatomy theatre.

    Lange Sint Agnietenstraat1 to 2 hours
  2. 02

    Academy Building and the "Sweat Room"

    The heart of the university on the Rapenburg. In the Zweetkamertje, doctoral candidates wait for the verdict and then sign the wall, next to generations before them.

    Rapenburg 73Half an hour
  3. 03

    Hortus botanicus Leiden →

    The oldest botanical garden in the Netherlands, with the Clusius garden, glasshouses and centuries-old trees.

    Rapenburg1 to 2 hours
  4. 04

    Old Observatory

    The 1860 observatory on the edge of the Hortus, successor to the rooftop observatory of 1633. Check the university website for open days.

    Sterrenwachtlaan15 minutes
  5. 05

    Museum De Lakenhal →

    Early work by Rembrandt, who was briefly a Leiden student, and the history of the city.

    Oude Singel1 to 2 hours
  6. 06

    Walk along the Rapenburg

    Often called the most beautiful canal in the Netherlands, with university buildings, the Hortus and old student houses.

    Rapenburg1 hour
Hidden story

Ehrenfest's wall

In a Leiden house there is a wall covered in the signatures of the greatest physicists of the 20th century.

Read the storyHide the story

Paul Ehrenfest succeeded Lorentz as professor of physics in Leiden. His home became a meeting place for scientists from all over Europe. Guests who stayed were asked to write their name on the wall of the guest room. That is how it came to carry the signatures of, among others, Albert Einstein and Niels Bohr. The house is privately owned and cannot be visited, but the story shows how small and lively the world of science was then, and how Leiden stood at its centre.

Where: Witte Rozenstraat, Leiden (private house)

Beyond the city

Three day trips to science and art nearby.

Train from Leiden Centraal, approx. 15 to 20 min

Haarlem

Teylers Museum, the oldest museum in the Netherlands, full of fossils, instruments and drawings.

Route by public transport ↗

Travel times are indicative. Live times on 9292.nl ↗.

SLEEP

Stay in Leiden, the city of knowledge

Leiden is small enough to walk everywhere. The Hague, Delft and Haarlem are a short train ride away.